Your opinion about running 2 AV program?

Thanks very much for your suggestion.

 

As stated, 2 active AV programs will cause issues, your machine can lock up, slow down, as well as refuse to boot (2 AV programs fight for control of the computer). I've seen ANY combination cause your OS not to boot, you'll just get 7B BSOD. Anti-malware works different, in fact I highly recommend Malwarebytes and an AV.

 

But even for Malwarebytes Pro (active protection as opposed to the free version) you have to makes exclusion in combo wth some AV programs.
See their forum: FAQ - Common Issues, Questions, and their Solutions - Malwarebytes Forum
Highly recommend Malwarebytes and Hitmanpro as second opinion scanner.
Malwarebytes : Free anti-malware, anti-virus and spyware removal download
Hitman Pro 3 - SurfRight

 

Yes, correctly, one anti-virus program and anti-malware program with no real-time protection.

 

I used to run Microsoft Security Essentials with Spyware Doctor from the Google Pack. It served me well, but now I'm running MSE by itself.

 

No problems running MSE and Malwarebytes (the non-real-time version). No problems.

 

Sorry, late to the party here - there's a difference between a product like Malwarebytes and, say MSE or Norton. MWB (free edition) doesn't hook into the OS kernel and doesn't intercept system calls like "traditional" antimalware software. That's why you can have, say, Norton Internet Security and MalwareBytes installed on a machine at the same time. My guess is the paid MWB probably adds more traditional detection methods into the mix (realtime scanning), which will cause issues with other security software.

TLDR: never ever ever install two antimalware products that have realtime scanning. Bad juju.