I downloaded and installed the OS X Mavericks Developer Preview earlier and so far, so good. I haven't run into any major problems yet, but I also haven't been able to do any extensive testing. So far, the only app that won't run on Mavericks is Symantec Endpoint Security. However, as I got this through a service provided by the US Government and I also happen to know the chief of operations at TRADOC IMD, I may be able to find out if there is a beta available for either Symantec Endpoint Security or McAfee Enterprise. I have installed Microsoft Office 2011, various apps from the Mac App Store, and Google Chrome. I haven't tested any of the Office applications yet. The one app from the App Store that I tested was Raiden Legacy and that ran without problems. Google Chrome also runs just fine. As I test out Mavericks more, I will update on app compatibility issues and bugs in the software.