Long shot but I'd just post here the problem I've been having intermittently and lately all the time with an m220 mouse. It would cut out at times, seemed to be when I had something plugged into the usb next to the receiver but now it is still doing it with nothing in the usb next to it. Cuts out, goes dead, comes back here and there, sometimes nothing. Tried other usb slots same, take out battery, new battery, same, different laptop same but seems to work better there but I use that one only here and there for video out. I use my other wireless mouse in the same usb no problems. It's about 2 years old and I'm not a power user, don't game with kbm at all, only gamepad.